Figure 3

Binding activity of p-CREB in nuclear extracts assessed by EMSA. The part a showed the excess of unlabeled p-CREB probes and unlabeled mutational p-CREB probes abolished binding, demonstrating the specificity of all binding complexes. Binding activity of p-CREB among the control, model, and EA groups was shown in the part b. Arrows indicated the binding of p-CREB and the free probe.