Fig. 4

RE reversed LPS-induced cognitive impairment in rats in a sex dependent manner. A MWM represented by latency time to reach the platform over 5 training days, AUC and removal phase 24 h after the last training day; B EPM score represented by the time to reach the reservoir at 0 h (training), 1 h (acquisition) and 24 h (retention) as well as AUC. Data are presented as the mean ± SEM. (∗ P < 0.05; ∗  ∗ P < 0.01; ∗  ∗  ∗ P < 0.001 compared to control, # P < 0.05 ## P < 0.01 compared to LPS)