Fig. 5

A The extracelluar glutamate level in the IE group was higher than that in the sham, TAT-Gap19-IE or siRNA Cx43-IE group. The extracelluar glutamate level in the in the TAT-Gap19-IE group was lower than that in the TAT-Gap19I130A-IE group. The extracelluar glutamate level in the siRNA Cx43-IE group was lower than that in the nontargeted siRNA-IE group. B The extracelluar ATP level in the IE group was higher than that in the sham, TAT-Gap19-IE or siRNA Cx43-IE group. The extracelluar ATP level in the TAT-Gap19-IE group was lower than that in the TAT-Gap19I130A-IE group. The extracelluar ATP level in the in the siRNA Cx43-IE group was lower than that in the nontargeted siRNA-IE group. **p < 0.01, ****p < 0.0001. Data represents means ± SD, n = 6