Fig. 2

Elevated Plus Maze (EPM). (A) Time spent in the open arms (B) Time spent in the center (C) Number of entries into the open arms relative to total number of entries into the open and closed arms (D) Total number of entries into open and closed arms (E) Anxiety index (see Methods) (F) Total distance traveled. Box central marks indicate the median, bottom and top edges indicate the 25th and 75th percentiles, n = 10–12 / group, asterisks denote the effect of genotype *p < .05, **p < .01, ***p < .001, ns non-significant