Fig. 4

Immunohistochemistry staining and quantification of β-tubulin (A) and MAP2 (B) in the hippocampus of infected animals compared to control and sham groups (50 μm). C. acnes infection decreases β-tubulin and MAP2 expression. The samples were counterstained with DAPI (blue). All data are indicated as the mean ± SD (n = 3 for each group), ****p < 0.0001, ***p < 0.001 and **p < 0. 01