Skip to main content

Table 2 Multivariate ANOVA investigating association of genotype, sex, and treatment with behaviour

From: Host genetics maps to behaviour and brain structure in developmental mice

Test

Parameter

Effect

df

F

Sig

Righting reflex

Average righting reflex

Genotype

5

130.2

 < 0.001

Genotype * sex

5

3.8

0.002

USV

USV calls

Genotype

5

127.6

 < 0.001

USV duration

Genotype

5

115.3

 < 0.001

Genotype * treatment1

5

2.5

0.027

USV ICI

Genotype

5

60.6

 < 0.001

Eye opening

Eye opening Score

Genotype

5

30.0

 < 0.001

Open field

OF rearing

Genotype

5

69.1

 < 0.001

Combined treatment

3

6.8

 < 0.001

Genotype * treatment

15

2.2

0.005

Genotype * sex

5

3.8

0.002

OF total distance

Genotype

5

86.5

 < 0.001

Combined treatment

3

4.5

0.004

Genotype * treatment

15

2.8

 < 0.001

Genotype * sex

5

5.4

 < 0.001

Sociabilty

Center chamber

Genotype

5

77.2

 < 0.001

Empty chamber

Genotype

5

3.9

0.002

Mouse chamber

Genotype

5

31.9

 < 0.001

Sex * treatment

3

3.0

0.031

Grooming

Grooming duration

Genotype

5

43.3

 < 0.001

Grooming frequency

Genotype

5

29.9

 < 0.001

Genotype * sex

5

2.8

0.016

Sex * treatment

3

3.5

0.015

Grooming latency

Genotype

5

7.3

 < 0.001

Genotype * sex

5

3.3

0.006

  1. 1Treatment only refers to P3 treatment (LPS or SAL), as developmental milestone is assessed before P9 treatment (CON or MS)