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Fig. 5 | Behavioral and Brain Functions

Fig. 5

From: Imaging-validated correlates and implications of the pathophysiologic mechanisms of ageing-related cerebral large artery and small vessel diseases: a systematic review and meta-analysis

Fig. 5

Subgroup analysis according disease subtype. Using the measures of cerebral blood flow and CVR as the measures of cerebrovascular function in subgroup analyses: (a) Shows an overall negative effect size [SMD = − 0.85 (95% CI − 1.34, − 0.36)], which signifies a reduction in cerebrovascular functions in participants presenting exclusively with small vessel diseases. (b) Shows an overall negative effect size [SMD = − 2.09 (95% CI − 3.57, − 0.62)], which signifies a reduction in cerebrovascular functions in participants presenting exclusively with large arterial diseases. Schematic model for cerebral large artery and small vessel diseases. A simple diagram that could serve as a guide to explore the interconnectedness of underlying mechanisms implicated in cerebral large artery and small vessel diseases

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Behavioral and Brain Functions

ISSN: 1744-9081

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