Fig. 1

Experimental design and changes in anxiety behavior of male rats on the third day after exposure to acute noise of different intensities. (a) Timeline for experiment. (b) Representative motion trajectories of male rats in the OFT (top) and EMPT (bottom). (c) Total distance, (d) center zone time, (e) NO. of center zone entries in OFT after different sound pressure level of acute noise exposure. (f) Time spent in open arms, (g) EPM index, (h) Anxiety index in EPMT after different sound pressure level of acute noise exposure. N = 8–10 rats per condition. *P < 0.05, **P < 0.01, ****P < 0.0001