Fig. 6

Effects of 135dB acute noise exposure on blood brain barrier of male rats. (a) The content of S100β in hippocampus on the third day following exposure to acute noise at different intensities. (b) Expression levels of blood-brain barrier-related proteins in the hippocampus of male rats on the third day following exposure to acute noise at different intensities. Quantification of ZO-1 (c), Claudin-5 (d), and Occludin (e) protein expression. (f) Expression levels of blood-brain barrier-related proteins in the hippocampus of male rats one month after exposure to acute noise at 135dB. Quantification of ZO-1 (g), Claudin-5 (h), and Occludin (i) protein expression. N = 4 rats per condition. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001